Ahead of this match, the Liverpool homepage has listed 14 notable statistics.
Liverpool have met Inter six previous times in European competition, winning four and losing two.
Liverpool have the opportunity to become the second away team in history to beat Inter three times away in the European playground, after Bayern Munich.
The English side have won five of their last six away games against Italian clubs.
Cody Gakpo could have his 150th match for Liverpool. He has scored 46 goals since joining the team in January 2023.
Liverpool have won 7 of their last 9 away matches in Europe.
This is the ninth consecutive season that the English port city team has faced teams from Italy.
Dominik Szoboszlai and Virgil van Dijk have played every minute of Liverpool's Champions League campaign this season.
Conor Bradley will be suspended for the trip to Marseille in the new year if he receives a yellow card in the match against Inter Milan.
Arne Slot's side have lost just twice in their last 16 games on 9 December, a run that began in 1933. Those were 2 losses to Fiorentina in 2009 and to independiente in 1984 at the World Club Championship in Tokyo.
Inter are the last Italian team to win the Champions League, lifting the trophy in 2010 when they beat Bayern 2-0 in Madrid.
The Nerazzurri have reached the UEFA Champions League final two of the last two of the season but have lost both to Man City in 2023 and Paris Saint-Germain earlier this year.
Inter Milan have won four of their five Champions League games this season, conceding just three goals.
Lautaro Martinez has scored in each of Inter's last five home Champions League games, scoring eight goals in total. The Argentine striker has scored 12 goals in the last 12 matches in this tournament.
Inter are unbeaten in their last 18 home matches in Europe, a streak that has lasted since September 2022.
The Inter Milan vs Liverpool match will take place at 3:00 a.m. on December 10 (Vietnam time).