CVH patient (46 years old, from Thanh Hoa) went to Ho Chi Minh City to work as a construction worker at a project in Go Vap district. On the morning of June 5, 2024, while drinking morning coffee with colleagues, patient H. suddenly fell to the ground and stopped breathing.
After 5 minutes of shaking and not waking up, patient H. was taken by his colleagues by motorbike to Go Vap District Hospital for emergency treatment. After 10 minutes of arriving at Go Vap Hospital, the patient was admitted with unmeasured pulse and blood pressure. Mr. H. was resuscitated from cardiac arrest and continuously electroshocked for 30 minutes. Although natural circulation was restored, doctors assessed that patient H. was at high risk of brain death with dilated pupils on both sides. After explaining to his relatives the decision to continue resuscitation until the end, although hope was very slim, patient H. was contacted and immediately transferred to Gia Dinh People's Hospital.
Patient H. was admitted to the Department of Cardiovascular Resuscitation - Gia Dinh People's Hospital in a state of very severe metabolic acidosis, acute pulmonary edema and myocardial damage causing severe heart failure due to prolonged cardiac arrest.
MSc. Nguyen Thanh Thao, the patient's main treating doctor, said: "In that situation, Mr. H. received central hypothermia intervention to protect his brain from further damage and oxygenation was performed. Hybrid extracorporeal hemodialysis (V-AV ECMO) and continuous hemodialysis correct associated renal dysfunction. After 1 week of intensive resuscitation intervention, Mr. H.'s myocardial contractile function recovered almost completely, and lung damage after cardiac arrest improved significantly. Patient H. stopped ECMO intervention after 10 days and brain function began to show signs of recovery 2 weeks later."
MSc. Giang Minh Nhat - Deputy Head of the Department of Cardiovascular Resuscitation, Gia Dinh People's Hospital added: "With the comprehensive management process for patients who suddenly die due to external cardiac arrest, the patient is surveyed for the cause of the arrest. heart. Test results showed that patient H. had a frameshift mutation in the dominant gene titin TTN on the autosomal chromosome. Mutations in the TTN gene have recently received a lot of attention in the medical literature, as a cause of sudden death in cardiomyopathy." With clear results of the gene mutation causing the disease, his 3 biological children were also given genetic consultation by doctors and given a long-term cardiovascular monitoring strategy to prevent sudden death.
To prevent sudden cardiovascular death, for people with a family history of cardiovascular events, in-depth cardiovascular examination and evaluation is necessary. In addition, all people over 30 years old should have a habit of regular health check-ups to screen and adjust cardiovascular risk factors.
