Round 12 of the Premier League will open with Leicester City vs Chelsea; end with Newcastle vs West Ham.
Despite winning just one of their last five Premier League games, Chelsea are still third in the table ahead of the away game against Leicester City.
Chelsea will confidently consolidate that position as they have lost just one of their last seven Premier League away games against Leicester, winning their last two visits with a total score of 6-1.
Meanwhile, Leicester have not won in their last 13 top-flight games against top-placed sides, with 10 losses and conceding 35 goals in that worrying run.
According to Opta, Chelsea have a 59.5% chance of winning the match, while Leicester have only 19%.
Arsenal vs Nottingham is another notable match on November 23. The Gunners have won six of their last seven league games against Forest and have won their last four at home.
But Arsenal have picked up just two points from their last four games ahead of the clash and are on their worst winless run in the competition since a run of seven consecutive games without a win at the end of 2020.
However, the Opta supercomputer is still confident in Arsenal's chance to get back on track, given a 67.6% chance of winning - a higher rating than any other home team this week.
While Forest have just a 13.7% chance of winning all three points at the Emirates.
For Man City, one of their four consecutive defeats came against Tottenham in the League Cup. This round, Pep Guardiola's team will host their opponents at home.
Spurs have not been very convincing in recent away games, having won just two of their last 11 away games in the Premier League and suffering seven away defeats since March 2024.
According to Opta's prediction, Man City have a 60.1% chance of winning, while Spurs have only a 19.8% chance and will probably be satisfied if they can get a draw (20.1%).
Liverpool are expected to have an easy game at Southampton. Liverpool have won 10, drawn three and lost just one of their last 14 Premier League meetings with Southampton, with Mohamed Salah entering the game in fine form.
The striker has been directly involved in 14 of Liverpool's 21 goals in the league this season (eight goals and six assists), the highest tally by a player for any team in 2024-25.
Man United also have a match that is predicted to be easy at Ipswich, in the debut of coach Ruben Amorim.
Despite a turbulent few years, one thing Man United have always done well is get points against promoted sides.
The Red Devils have won 17 of their last 19 top-flight games against promoted sides and drawn the other two. away, Man United are also on a 9-match winning streak against rookie teams.
Amorim has limited time to deploy his coaching methods, but the supercomputer Opta believes he has a good chance of getting off to a good start.
According to Opta's prediction, Ruben Amorim will have a smooth start with Man United, with a probability of winning at 54.8%, while Ipswich have a 22.2% chance of winning this match.
