Round 12 of the Premier League will open with Leicester City vs Chelsea; ending with Newcastle vs West Ham.
Despite winning just one of their last five Premier League games, Chelsea remain third in the table ahead of their away game against Leicester City.
Chelsea will be confident of consolidating that position as they have lost just one of their last seven Premier League away games against Leicester, winning their last two visits by an aggregate score of 6-1.
Meanwhile, Leicester are winless in their last 13 top-flight games against teams at the top of the table, losing 10 and conceding 35 goals in that worrying run.
According to Opta, Chelsea will have a 59.5% chance of winning the match, while Leicester only has a 19% chance.
Arsenal vs Nottingham is another notable match on November 23. The Gunners have won 6/7 of their most recent league matches against Forest and have won their last 4 home games.
But Arsenal had picked up just two points from their last four games before this clash and were on their worst winless run in the league since a run of seven straight games without a win at the end of 2020.
However, the Opta supercomputer is still confident in Arsenal's chances of getting back on track, with them given a 67.6% probability of winning - a higher rating than any other home team this week.
Meanwhile, Forest only have a 13.7% chance of winning 3 points at Emirates Stadium.
For Man City, one of their four consecutive defeats came against Tottenham in the League Cup. This round, Pep Guardiola's team will host their opponents at home.
Spurs have not been particularly convincing on the road recently, winning just two of their last 11 Premier League away games and suffering seven away defeats since March 2024.
According to Opta's predictions, Man City have a 60.1% chance of winning, while Spurs have just a 19.8% chance and would probably be satisfied if they could get a draw (20.1%).
Liverpool are expected to have an easy game at Southampton. Liverpool have won 10, drawn three and lost just one of their last 14 Premier League meetings with Southampton and Mohamed Salah comes into the game in fine form.
The striker has been directly involved in 14 of Liverpool's 21 league goals this season (with eight goals and six assists), the highest ratio by a player for any team in the 2024-25 season.
Man United also have an easy match predicted at Ipswich, in the debut match of coach Ruben Amorim.
Despite a turbulent few years, one thing Man United have always done well is pick up points against promoted sides.
The Red Devils have won 17 of their last 19 top-flight games against promoted opponents and drawn the other two. Away from home, United are also on a nine-match winning streak against newly promoted sides.
Amorim has limited time to implement his training methods, but the Opta supercomputer thinks he has a good chance of getting off to a good start.
According to Opta's prediction, Ruben Amorim will have a smooth start with Man United, with a 54.8% probability of winning, while Ipswich have a 22.2% chance of winning this match.
