Carlos Alcaraz and Aryna Sabalenka were seeded No. 1 before the main round of the Australian Open, while Jannik Sinner and Iga Swiatek were seeded No. 2.
Alcaraz and Sinner are facing the opportunity to become the first two men's tennis players to play 4 consecutive Grand Slam finals since Novak Djokovic and Rafael Nadal did so in the 2011-2012 period.
Alcaraz aims for his first Australian Open title in his career - a milestone that could turn him into the youngest player in history to complete his "Grand Slam career". On Sinner's side, the Italian player aims for a hat-trick title in Melbourne.
In the women's category, Sabalenka - US Open champion - and Swiatek - Wimbledon champion - have never met in a Grand Slam final. Swiatek also only needs the Australian Open to complete her "Grand Slam career", while Sabalenka will strive to regain the throne after a surprise fall to Madison Keys in last year's final.
In other notable developments, Coco Gauff participated in the first Grand Slam of the year as No. 3 seed, while defending champion Keys was No. 9 seed in the women's singles event.
Novak Djokovic, who holds a record of 10 championships in Melbourne, is the 4th seed in the men's singles and is predicted to face Alcaraz or Sinner in the semi-finals if they advance to this round.
Notably, Venus Williams - at the age of 45 - is preparing to become the oldest female tennis player to participate in the main round of the Australian Open, after the 7-a-side women's singles Grand Slam champion received a wildcard.
The Australian Open draw will take place on Thursday, January 15, at 2:30 PM (local time). The final qualifying round will also be held on January 15.