Israeli airstrikes across Gaza overnight and on September 11 (local time) hit a United Nations school - a shelter for displaced Palestinian families - along with two homes, killing at least 34 people, AP reported citing information from hospital officials.
A United Nations official said six of its staff were among the dead.
In the occupied West Bank, the Israeli military carried out raids and airstrikes on several towns. One airstrike killed five people, who the Israeli military said were Hamas militants. A second attack on a car killed at least three people, the Palestinian Ministry of Health said.
Meanwhile, an attacker rammed a fuel truck into a bus station in the West Bank, near the Israeli settlement of GIvat Assaf, killing one Israeli soldier. The attacker was subdued.
An attack on the United Nations Al-Jaouni Boys' Preparatory School in the Nuseirat refugee camp left at least 14 people dead, including two children and a woman, and at least 18 others injured, officials from Awda and al-Aqsa Martyrs Hospital said. According to the Israeli military, the attack targeted Hamas members who were planning an attack from inside the school.
One of the children killed was the daughter of Momin Selmi, a member of the Gaza civil defense agency, which rescues the wounded and recovers bodies after airstrikes.
Schools in Gaza are packed with tens of thousands of Palestinians displaced by Israeli attacks. Al-Jaouni School, one of several schools in Gaza run by the United Nations Relief and Works Agency for Palestine Refugees (UNRWA), has been hit multiple times during the fighting. UNRWA said six staff assisting displaced people, including the shelter manager, were killed.
Earlier on September 11, an airstrike hit a house near the city of Khan Younis in southern Gaza, killing 11 people, including six siblings aged between 21 months and 21 years, according to the European Hospital, which received the casualties.
The war in Gaza is now in its 11th month, with tens of thousands of people killed and international efforts to broker a ceasefire between Israel and Hamas repeatedly stalled.