High blood pressure
Sitting for long periods of time reduces muscle contraction, affecting blood circulation. When blood stagnates in the lower limbs, blood circulation slows down, leading to increased pressure in the arteries and veins. This can lead to higher than normal blood pressure levels.
When blood pressure increases, the heart has to work harder to pump blood to the rest of the body. Over time, this stress can thicken and widen the left ventricle of the heart, increasing the risk of heart attack and heart failure.
Increased inflammation
Lack of exercise contributes to inflammation throughout the body. Chronic inflammation damages blood vessels and accelerates atherosclerosis, which is the buildup of plaque in the arteries. The buildup of plaque inside the arteries reduces blood flow and increases the risk of stroke, heart attack or other heart-related conditions.
Causes insulin resistance
Lack of exercise weakens the body's ability to regulate blood sugar levels, leading to insulin resistance. Untreated insulin resistance can lead to type 2 diabetes, characterized by chronic high blood sugar. Over time, high blood sugar will damage blood vessels and the heart muscle.