According to Doctor Hoang Minh Khoa II - Xanh Pon General Hospital (Hanoi), when cells die, their fillings are destroyed and converted into endogenous uric acid. Uric acids that come from foods such as meat, fish or some other metabolic paths are of exogenous origin.
Every day, excess uric acid will be excreted from the body through urine about 80% and 20% through the digestive tract and sweat.
hyperuricemia is a condition in which uric acid levels in the blood increase by more than 6.0 mg/dl (for women) and 7.0 mg/dl (for men).
Uric acid is a product of the breakdown of purine - a substance found in many foods and is also naturally produced in the body.
When the body produces too much uric acid but cannot excrete it through urine, uric acid levels in the blood will increase, leading to increased uric acid in the blood.
High uric acid in the blood can lead to the formation of urate crystals, accumulate in joints and cause gout, about 10-15% of people with high uric acid are simply at risk of gout. High uric acid levels can also cause kidney stones and other kidney diseases.
Causes of increased uric acid in the blood
Diet: Consuming a lot of purine-rich foods such as red meat, seafood (especially salmon, shrimp, lobster, sardines), animal organ covers, especially dog meat and alcoholic beverages, especially beer (including non-alcoholic beer), beverages with corn syrup with high sugar content, etc., can increase uric acid levels in the blood.
Genetics: Some people with a genetic trend in the family are more susceptible to hyperuricemia than others.
Obesity: Obese people are often at high risk of hyperuricemia because the body produces more uric acid and has difficulty eliminating them.
Medications: Some medications such as diuretic drugs (furosemide), corticoids, low-dose aspirin, anti-tuberculosis drugs (Ethambutol, Pyrazinamid) and immunosuppressants can increase uric acid levels in the blood.
Diseases: Diseases such as kidney failure, blood disease, metabolic syndrome, enzyme deficiency in purine metabolism (genetic diseases) and some cancers can also cause this condition.
sedentary lifestyle: A sedentary lifestyle can contribute to increased risk of obesity and metabolic problems, leading to increased uric acid in the blood.
Not drinking enough water, staying urinary: About 80% of uric acid is excreted in the body through urine. Not drinking enough water and urinating is the reason why uric acid is not excreted but will accumulate back.
Increased uric acid in the blood is a serious health problem but can be effectively managed through lifestyle changes, diet and drug use. Understanding the cause will help you prevent and control this condition in the best way. Maintain a healthy diet, drink enough water, exercise regularly and follow your doctor's treatment advice to keep uric acid levels in your blood at a safe level.
