Right from the start of the match, Inter proactively imposed their playing style and created great pressure. The turning point came in the 30th minute when goalkeeper Jindrich Stanek made an inaccurate passing mistake, creating conditions for Lautaro Martinez to finish close to the opening goal.
Just a few minutes later, Marcus Thuram broke through on the left wing before helping Denzel Dumfries double the gap. The home team ended the first half with a 2-0 advantage.
After the break, Inter continued to maintain an encroachment. In the 65th minute, in a quick counter-attack, Alessandro Bastoni crossed accurately for Martinez to complete his double, setting the score at 3-0.
In the remaining minutes, Inter took many key players off, while Slavia could hardly make a difference. The visitors' most notable chance was a long-range shot by Muhammed Cham in the 80th minute but could not beat goalkeeper Yann Sommer.
With 6 absolute points after two matches, Inter temporarily rose to the top of the group. Lautaro Martinez became the biggest bright spot when he directly scored two goals, showing his role as the leader of the attack.
Meanwhile, Slavia Prague continued to extend their away winless streak against Italian teams in the European Cup to 9.
The convincing victory gave Inter more confidence before returning to Serie A this weekend to Cremonese.
With their current form, coach Chivu's team shows that they are ready to become a deep competitor in the Champions League this season.