Ben White could be out for around six weeks after undergoing knee surgery, which could hamper his chances of playing time this season. Depending on how his recovery progresses, the right-back could return sooner than expected.
Other Gunners defenders Riccardo Calafiori and Takehiro Tomiyasu are also fighting to be fully fit before December, with the Italian aiming to return in the coming weeks. The Japanese defender's future remains unclear after suffering a number of injury setbacks in pre-season.
Despite a string of injuries, Mikel Arteta and the Arsenal board currently have no specific transfer targets for the winter.
Chief executive Richard Garlick made a routine trip to the United States this week to meet owner Stan Kroenke and co-chairman Josh Kroenke. The meeting was aimed at planning for next summer's transfer window and was held without sporting director Edu after he resigned last week.
Arsenal's policy, however, remains the same - January is a time to be reactive rather than proactive, with their last big spend in the January transfer window coming in the 2022-23 season.
They spent money two years ago to recruit Brighton's Leandro Trossard, Chelsea's Jorginho and Spezia's Jakub Kiwior for around £40m.
Arteta's injury worries have eased in recent weeks with captain Martin Odegaard returning to action, while Mikel Merino, Jurrien Timber and Gabriel have also proven their fitness.
Arsenal have made a number of moves this summer, including the £27m signing of goalkeeper David Raya after a season-long loan spell from Brentford.
They also signed Calafiori for £42m and spent £32.6m on Merino from Real Sociedad. The loan signings of goalkeeper Neto and Raheem Sterling on transfer deadline day also helped to create competition in the Arsenal squad.
There were also sales of Emile Smith Rowe to Fulham and Eddie Nketiah to Crystal Palace, as well as goalkeeper Aaron Ramsdale moving to Southampton.
Arsenal return from FIFA Days in November to face Nottingham Forest, currently fifth in the Premier League, with Arteta's side looking to prove their mettle after a difficult start to the season.