The fire at a COVID-19 patient treatment facility broke out at 5am, with 22 patients being treated at the hospital at the time of the incident.
Some people trapped and injured were rescued and taken to the hospital. The fire was brought under control but rescue operations were still ongoing, said a police officer.
Home Secretary Amit Shah expressed his sadness at hearing the news of the fire. Minister Amit Shah expressed his condolences to the families of the deceased victims and prayed for a speedy recovery for the injured.
Andhra Pradesh head of state, Jagan Mohan Reddy, has directed officials to conduct an investigation into the hotel fire, ANI reported.
Last week, eight COVID-19 patients died in a fire at a private hospital's special care unit in Ahmedabad, western India.