A US official described it as a "large-scale" attack targeting 70 targets in areas of central Syria, where there is IS infrastructure and weapons.
Another US official said more attacks are expected after the attack on Syria on December 19.
The latest US attack on Syria was carried out by F-15 Eagle fighter jets, A-10 Thunderbolt ground attack aircraft and AH-64 Apache helicopters. Jordan's F-16 fighter jets and HIMARS rocket artillery were also used in the attack.
The latest US attack on Syria was in retaliation for an ambush attack that killed two US soldiers and an American interpreter nearly a week earlier.
This is not the beginning of a war but a statement of vengeance. The United States, under President Trump's leadership, will never hesitate and never falter in protecting our people, Secretary of War Pete Hegseth said.
