Man City are going through their worst period of form since coach Pep Guardiola took over.
They have conceded seven goals in their last two Champions League games and are currently 17th in the table with just eight points, just enough to qualify for the play-offs.
The Citizens have reached the knockout stages in each of the last 11 seasons, finishing top of the table in seven consecutive seasons. Now, with the new format, breaking into the top eight has become a tough challenge, especially given City's recent poor results.
They travel to Italy having won just one of their last nine games in all competitions, and it will be the first time City have faced Juventus under Pep Guardiola.
Like their opponents, Juventus are also on 8 points and are 19th in the Champions League standings. Thiago Motta's team are not playing badly, but the problem is that they draw too many times. Since the beginning of the season, they have had 19 draws, so their position in Serie A and Europe is average.
The Bianconeri have now drawn four consecutive games in all competitions, including seven in their last nine outings. The Turin giants can be confident of hosting the English champions with the best defensive record in Serie A, having conceded just 10 goals and kept 10 clean sheets in 15 games.
Expected lineup
Juventus: Perin; Savona, Kalulu, Gatti, Danilo; Locatelli, Thuram; Conceicao, Koopmeiners, Weah; Vlahovic
Man City: Ortega; Walker, Dias, Gvardiol, Lewis; Gundogan; Savinho, De Bruyne, Silva, Nunes; Haaland