The role of platelets in the body
Subcutaneous platelets are small, colorless pieces of blood cells produced in the bone marrow. The main role of platelets is to help blood clot, prevent excessive bleeding and support the blood holding process when there is damage to blood vessels. Substants not only play an important role in blood clotting but also in maintaining healthy blood vessels.
thrombocytopenic production process
According to Dr. Mallikarjun Kalashetty - consultant in Hematology, Blood Agency and Marrow graft, Manipal Old Airport Road Hospital (India), platelets are made from stem cells that create blood in bone marrow, developing into large megakaryocytes. megakaryocytes break down into small pieces, form platelets and release into the blood. This process is regulated by the hormone thrombopoietin (TPO), which helps stimulate the maturity of megakaryocytes and platelet production. Substants play an important role in blood clotting.
What is the normal platelet count?
Dr. Mallikarjun Kalashetty says that the normal number of platelets in the body ranges from 150,000 to 450,000 platelets per microliter of blood. When platelet count drops below 20,000-30,000 platelets per microliter, it can lead to severe bleeding symptoms due to reduced blood clotting ability.
Causes of thrombocytopenic purpura
thrombocytopenia is a condition in which the number of platelets in the blood is lower than normal, causing the risk of bleeding and blood clotting problems. There are many causes of thrombocytopenic purpura, including:
Poor platelet production: This can happen when bone marrow does not produce enough platelets. Disorders such as white blood disease, anemia, or the consequences of chemotherapy and radiotherapy can reduce platelet production.
Excessive thrombocytopenic purpura: Some autoimmune diseases such as immune thrombocytopenic purpura (ITP) cause the body to attack and destroy platelets. Some infections and medications can also lead to increased platelet destruction.
audience members are stuck: Sub place cards can be stuck in the spleen, leading to reduced platelet count in the blood. This can happen in diseases such as cirrhosis, cancer or increased pressure in the cua vein.
Symptoms of thrombocytopenia
Depending on the severity of thrombocytopenia, symptoms can range from mild to severe, including:
facility of bruising and bleeding under the skin
Frequent orange bleeding
Internal bleeding (stomach or visceral bleeding)
Prolonging the time for blood clotting when there is a wound
Note
Dr. Kalashetty emphasizes that early monitoring and treatment are important to maintain safe platelet count and avoid side effects related to drugs. Early diagnosis and timely treatment can help prevent serious complications related to thrombocytopenia.
