Star anise plants contain many biologically active compounds such as flavonoids, phenolic acid, lignans and minerals such as potassium and magnesium. According to a general report published in the Journal of Herbal Medicine, these compounds have strong antioxidant properties, helping to reduce oxidative stress - a factor contributing to increasing uric acid production in the body.
WHO also notes in traditional medicine documents that nettle has a natural diuretic effect, supporting increased excretion of waste through urine, including uric acid. The high potassium content in the plant helps regulate electrolyte balance and supports the kidney's filtration function.
Uric acid is formed from the purine metabolism and is excreted by the kidneys. When this process is interrupted, the level of uric acid in the blood increases, leading to the risk of gout.
Preclinical studies show that centipede can affect both mechanisms: reduced production and increased uric acid excretion.
In addition, the diuretic properties of nettle help increase urine flow, thereby supporting the kidneys to eliminate uric acid more effectively.
An analysis published in Frontiers in Pharmacology shows that flavonoids in the umbilical cord can improve kidney tube function and reduce uric acid reuptake, contributing to reducing the concentration of this substance in the blood.
Not only affecting uric acid, centipede also has anti-inflammatory effects - an important factor in controlling gout symptoms. Compounds such as quercetin in plants have the ability to inhibit inflammatory cytokines.
According to the European Medicines Agency, rosemary extract has been used in some herbal preparations to support pain relief and arthritis.
This is especially meaningful for people with prolonged hyperuricemia, when urate crystals accumulate in the joints causing pain and inflammation.
Note that nettle plants can interact with diuretics, antihypertensive drugs, or gout medications. People with chronic kidney disease, pregnant women, or those taking medication should consult a doctor before regular use.