At 4:30 p.m. on October 6, Vietnam time, the 2025 Nobel Prize in Biology and Medicine was announced by the Nobel Prize in Literature at the Karolinska Institute, Stockholm, Sweden, honoring two American scientists Mary E. Brunkow, Fred Ramsdell and Japanese scientist Shimon Sakaguchi for "their discoveries related to peripheral immunosupportation".
Three scientists Mary E. Brunkow, Fred Ramsdell and Shimon Sakaguchi will jointly share awards for their research on how to prevent the immune system from harming the body.
The three Prize-winning scientists have identified "regulating T cells" that function like the force that protects the immune system and prevents immune cells from attacking the body.
Their findings are decisive for our understanding of how the immune system works and why not all of us suffer from serious autoimmune diseases, said Nobel Committee Chairman Olle Kampe.
Ms. Mary E. Brunkow, born in 1961, is a PhD at Princeton University, Princeton, USA. She is currently the Senior Program Manager at the Institute of Systematic Biology, Seattle, USA.
Mr. Fred Ramsdell, born in 1960, is a PhD from the University of California, Los Angeles, USA. He is currently a Science Advisor for Sonoma Biotherapeutics, San Francisco, USA.
Mr. Shimon Sakaguchi, born in 2015, was a medical doctor in 1976 and a PhD in 1983 at Kyoto University, Japan. He is currently a professor at the Center for Pioneering Campaign Studies, Osaka University, Japan.
Previously, in 2024, the Nobel Prize in Bi medicine was also awarded to two American scientists - Professor of Natural Sciences Victor Ambros at the University of Massachusetts Medical School and Professor of Genetics Gary Ruvkun at Harvard Medical School - for their work on the discovery of microRNA - the protein protein control of cells in the body.
