Overview
Real Betis are currently 16th in the Europa League table after three games, with one win and two draws in the opening stages.
Los Verdiblancos started the European campaign with a 2-2 draw with Nottingham Forest, in which Antony's 85th-minute equalizer helped the home team regain a valuable point at La Cartuja.
Manuel Pellegrini's side then won convincingly 2-0 against Ludogorets Razgrad, thanks to Giovani Lo Celso and Son's own goal.
Their most recent Europa League match ended in a goalless draw against Genk.
In the domestic league, Betis started strongly in La Liga 2025-2026, when they were in fifth place with 19 points after 11 matches (5 wins, 4 draws, 2 losses). Pellegrini's team also showed impressive scoring form when scoring 10 goals in the last two matches. Including a 7-1 victory over Atletico Palma del Rio in the Copa del Rey, followed by a 3-0 victory over Mallorca last weekend.
After reaching the UEFA Conference League final last season and winning the runner-up position, Betis is eager to advance further in the Europa League this season. They have only lost once in their last 11 matches in all competitions and will try to maintain that momentum of success in upcoming matches.
Meanwhile, Lyon arrived in Spain with impressive form in the European arena. Paulo Fonseca's side are third in the Europa League table with a perfect record after three games, scoring five goals and being one of only two teams yet to concede in the competition.
Lyon opened the campaign with a narrow 1-0 win over Utrecht, with the decisive goal scored by substitute Tanner Tessmann. They then won 2-0 against Red Bull Salzburg, before beating Basel 2-0 thanks to goals from Corentin Tolisso and Afonso Moreira.
While Europe has improved, Lyon's domestic campaign has been unstable. They are currently sixth in Ligue 1 with 20 points after 11 matches (6 wins, 2 draws, 3 losses).
Disciplinary issues are a concern for them, as this team received a red card in the last 2 matches in the tournament - against Brest and Paris FC. This raises questions about Lyon players' calmness in the face of tense matches in Europe.
Personnel situation
Real Betis have yet to have the service of midfielder Isco, who is recovering from a long-term leg injury.
Antony continues to be one of Betis' bright spots this season, with 5 goals and 2 assists after 9 appearances. The Brazilian player is expected to continue to maintain his position in the attack.
Ricardo Rodriguez was forced off early in the first half of the match against Mallorca due to a muscle injury, and the possibility of playing in this match is still uncertain. Meanwhile, Junior Firpo is definitely absent due to a hamstring injury, while goalkeeper Pau Lopez is also suspected of health problems.
On the Lyon side, Tanner Tessmann only played for 15 minutes in the draw with Brest before being forced off the field and will likely not be able to participate.
Orel Mangala and Ernest Nuamah are both out for long periods with cross-leg injuries, while Malick Fofana is out with ankle flaccidity.
Up front, Martin Satriano could be deployed as a starting forward, supported behind by Pavel Sulc. Meanwhile, Corentin Tolisso is expected to continue to play a pivotal role in midfield.
Expected lineup:
Real Betis: Valles, Ruibal, Bartra, Gomez, Bellerin, Amrabat, Fornals, Antony, Lo Celso, Ezzalzouli, Hernandez.
Lyon: Greif, Vinicius, Niakhate, Mata, Maitland- Ni Ni Niles, Carvalho, Morton, Moreira, Tolisso, Sulc, Satriano.
The match between Real Betis and Lyon takes place at 3:00 am on November 7 (Vietnam time).
