1. Dehydration
Although dehydration is not often mentioned as a cause of gout, it does not mean that it does not affect the disease. Dehydration reduces the kidneys' ability to excrete uric acid, leading to higher levels of uric acid in the blood, which can cause gout attacks.
2. Exposure to lead
Exposure to lead may increase the risk of gout. Lead can interfere with the kidneys' ability to excrete uric acid, leading to a buildup of uric acid in the blood and the formation of urate crystals.
3. Surgery and trauma
Surgery or trauma can trigger gout attacks. The stress response to surgery or trauma can lead to changes in the body's metabolism, dehydration, and decreased kidney function. All of these can increase uric acid levels and cause gout attacks.
4. Lose weight fast
Gradual weight loss is often beneficial for gout control, but rapid weight loss can have the opposite effect. Rapid weight loss, especially through crash dieting or severe calorie restriction, can lead to increased breakdown of body tissue, increasing uric acid levels and triggering gout attacks.
5. Fructose consumption
Fructose is found in sugary drinks and processed foods, so it can increase uric acid production when metabolized by the liver. Unlike glucose, fructose metabolism leads to increased purine production, which can then be converted to uric acid and increase the risk of gout.
