According to information on ScienceDirect - the world's leading scientific knowledge platform belonging to the publishing group Elsevier (Netherlands) - it is confirmed that perilla frutescens contains abundant concentrations of Phenolic and Flavonoid compounds.
In the intracellular environment, these active ingredients act as free radical collectors, neutralizing oxidative reactions caused by ultraviolet (UV) rays and environmental pollution. This mechanism directly prevents the degradation of the collagen and elastin networks in the dermis, helping to maintain the integrity of the cell DNA structure and slow down early aging manifestations from within.
Notably, the pigment Anthocyanin in purple perilla leaves is identified by experts as a potential antioxidant compound capable of protecting the subcutaneous microvascular system.
Scientific evidence shows that Anthocyanin supports the biosynthesis of natural antioxidant enzymes, helping to significantly improve elasticity and hydration (hydration) of the epithelium. This effect not only brings aesthetic value but also strengthens the skin's resistance to biological pressures, helping the skin surface always be stable and firm.
In the field of therapy, derivatives such as Rosmarinic Acid and Luteolin in perilla have shown clear immune regulation ability.
According to review reports on ScienceDirect, these active ingredients inhibit the release of inflammatory cytokines and minimize mast cell activity in releasing histamine.
Clinical results show that perilla extract can quickly soothe irritation reactions, reduce edema and support lipid barrier recovery for cases of atopic dermatitis (Eczema) or chronic contact dermatitis.
However, this pharmacological effect depends closely on the heat treatment process. Studies recommend that tea or perilla extract should only be brewed at temperatures from 80°C to 90°C to preserve essential oils and active ingredients that are less resistant to heat.
The application of perilla into modern health care and pharmaceutical and cosmetic products not only inherits the quintessence of traditional medicine but is also a sustainable and safe solution verified by the most stringent scientific standards today.