The statement came after Israeli Prime Minister Benjamin Netanyahu pledged to retaliate against Iran, after the Houthis launched a missile near Israel's Ben Gurion International Airport.
Responding to Iran's state broadcaster, Nasirzadeh stressed: "If this war is initiated by the US or Israel, Iran will target its interests, bases and forces - anywhere and at any time considered necessary."
According to Iran, the missile and drone attacks by the Houthis were independent acts, although the group is considered a close ally of Tehran. Nasirzadeh insists the Houthi forces are operating on their own motives.
The latest missile launch on May 4 from Yemen, claimed by the Houthis as a show of solidarity with Palestinians in Gaza, has further strained the regional situation.
The missile that fell near Ben Gurion airport is considered the latest sign of escalation in the recent series of attacks.
Responding on the X social networking platform, Israeli Prime Minister Netanyahu stated: The Houthi attacks originated from Iran. Israel will respond to the attack on our main airport and will act at the time and location chosen by us, targeting the terrorist masterminds in Iran.
Meanwhile, the US has carried out multiple airstrikes targeting Houthi bases in Yemen since March 15. US President Donald Trump also said he would hold Iran accountable for any actions by the group.
In addition to tough statements, Nasirzadeh insists Iran is not hostile to neighboring countries.
However, he stressed that in the event of an attack, US military bases in the area would become targets for Tehran.
Also on May 4, Iranian state media reported that the country had announced a new solid-fuel ballistic missile called the Qassem Bassir with a range of 1,200 km, demonstrating Tehrans growing military power amid escalating regional tensions.
