Long-term high-calorie diet
For people with high uric acid, focusing only on purines and alcohol in their daily diet is not enough. The amount of calories in the diet is also very important.
A high-calorie diet will make our body take in more calories than it consumes. If this condition persists, the consequences will be obesity.
Obesity can cause insulin resistance, glucose intolerance disorder, excessive adrenal cortical hormone... These factors will reduce uric acid excretion and increase purine metabolism.
Weight gain is a risk factor for gout, while weight loss can control uric acid levels and reduce the frequency of acute gout attacks. Therefore, people with high uric acid should choose a low-calorie diet and maintain a healthy weight.
Consume too much fructose
When the body metabolizes fructose, a series of reactions occur to stimulate and create uric acid, increasing the content of endogenous uric acid. At the same time, fructose also inhibits the excretion of uric acid through the kidneys. Therefore, too much fructose will cause the formation of uric acid.