Can methylen blue improve memory?
Green methylen is a synthetic dye invented in 1876, attracting the attention of the biohacking community thanks to claims to the ability to enhance memory and slow down the aging process. Although initially used to dye textiles, this substance is currently only approved by the US Food and Drug Administration (FDA) for use in the treatment of methemoglobinemia, a rare blood disorder that makes red blood cells unable to transport oxygen effectively.
Some preliminary studies show that methylen blue can improve body function and the energy-generating system of cells, which decline with age. This raises the possibility that methylen blue may help prevent cognitive decline and prolong life. However, evidence from human studies is still very limited.
Most of the current research is done on animals and is not strong enough to make a recommendation for widespread use, Dr. Nicole Kashfian, CEO of pharmaceutical retail at UCLA Health, told verywell Health. The scale of the studies is still small, short-term and has not proven to be effective in preventing aging or enhancing memory in humans.
Warning of risks when used incorrectly
A major concern is that using methylen blue along with depression medications such as SSRI can cause serotonin syndrome, a dangerous reaction that can lead to shakiness, diarrhea, sweating and even death. According to Jamie Alan, associate professor of pharmacology and toxicology at Michigan State University, other side effects include changing urine, skin and stools to green or green.
It may not be dangerous if given at the right dose, but the risk of drug interaction and misuse is huge, Alan warned. In addition, the likelihood of it being really effective is quite low, given the current data.
Another risk comes from functional foods containing green methylene of unknown origin. Because it is not approved by the FDA, consumers cannot know the actual ingredients or dosage. Some products may contain unknown impurities, causing poisoning, said Dr. Kelly Johnson-Arbor, a toxicologist at Med Star Georgetown University Hospital.
More worryingly, many medical spas are offering methylen blue vein transmission services for prices ranging from 150 to 450 USD, aiming to increase energy and improve awareness. However, these facilities often do not ensure safe medical conditions. I do not recommend using methylen blue at spas. Close medical monitoring is mandatory, but is often overlooked in these places," Johnson Arbor stressed.
Green methylene is not a " miraculous drug" as many people believe. Although it has potential in terms of biology, there is not enough scientific evidence to confirm the anti-aging or memory enhancement effects in humans. Before using any supplements, especially those not approved by the FDA, consumers should consult a health professional to avoid unnecessary risks.
