What is intermittent fasting and what is its mechanism?
Intermittent fasting is a method of eating intermittently between eating and fasting times, commonly like the 16:8 or 5:2 pattern. During fasting, the body switches to using stored energy, including glycogen and fat.
When the fat burning process takes place, the body produces ketones. This is a factor that can affect the uric acid excretion process. At the same time, this metabolic change also affects kidney function and endocrine balance.
Does intermittent fasting help reduce uric acid?
In the long run, intermittent fasting can help reduce uric acid indirectly through weight loss and improved insulin sensitivity. When weight is controlled, the body reduces uric acid production and increases kidney excretion.
However, in the early stages, especially when the body has not adapted, uric acid levels may temporarily increase. The reason is the process of cell breakdown and competition for excretion between ketones and uric acid in the kidneys.
Why can fasting increase uric acid in the short term?
When the body enters a state of fasting, the catabolism (dissolution) process takes place more strongly, increasing the production of endogenous purines - precursors of uric acid. This can cause uric acid levels in the blood to increase.
In addition, ketones born during fat burning will compete with uric acid in the kidney tubes, reducing the ability to excrete. This is why some people may experience acute gout attacks when starting to fast incorrectly.
Who should be careful when applying this method?
People with a history of gout, high uric acid or in the acute arthritis stage need to be especially careful. Sudden dietary changes can trigger symptoms and make the disease worse.
In addition, people with underlying conditions such as kidney failure, diabetes or metabolic disorders should also consult a doctor before applying it. Not every body is suitable for intermittent fasting.
How to apply safe intermittent fasting for people with high uric acid
If you want to apply it, patients should start with a short and gradually increasing fasting time for the body to adapt. Drinking enough water is very important to help the kidneys excrete uric acid more effectively.
During eating, it is necessary to prioritize low-purine foods such as green vegetables, whole grains and healthy proteins. At the same time, limit alcohol and sugary drinks to avoid increasing uric acid.
