Willow buds contain many bioactive compounds, among which salicin, flavonoids and polyphenols, phenolic acid are prominent.
These compounds have strong anti-inflammatory and antioxidant properties. Although direct research on willow buds is limited, studies on plant groups rich in polyphenols show that they can positively affect uric acid metabolism.
A recent scientific review confirms that compounds such as flavonoids and phenolic acids have the ability to reduce uric acid by inhibiting the enzyme xanthine oxidase and increasing urate excretion.
Studies on many medicinal plants with active ingredient structures similar to planthoppers provide an important scientific basis. For example: A 2026 study showed that plant extracts rich in polyphenols can reduce uric acid and protect the kidneys by regulating urate metabolism.
Other studies have noted that leaf extract helps regulate urate transporters in the kidneys and reduce inflammation, thereby improving hyperuricemia.
Plant compounds can also increase the expression of urate transporter proteins such as OAT1, ABCG2, helping to excrete uric acid through the kidneys and intestines.
These mechanisms are consistent with the biological properties of planthoppers, which are rich in polyphenols and anti-inflammatory compounds.
Willow buds can support uric acid control through three main mechanisms:
Inhibition of uric acid-creating enzymes
Xanthine oxidase is an enzyme that converts purines into uric acid. Polyphenols in planthoppers can inhibit this enzyme, thereby reducing uric acid production.
Increased kidney excretion
Biological compounds help regulate urate transporters in the kidney tubes, increasing uric acid secretion through urine.
Reduce inflammation and protect joints
Salicin in willow buds has an effect similar to aspirin, helping to reduce the inflammatory reaction caused by urate crystals - the main factor causing pain in gout.
Antioxidant and kidney-protective role
Oxygenated stress is an important factor that worsens kidney damage in people with hyperuricemia.
Polyphenols in willow buds help neutralize free radicals, protect kidney cells, and reduce the risk of fibrosis.
This is especially important because the kidneys are the main organs that eliminate uric acid.
Willow buds are commonly used:
Instill light drinking water.
Decoction with other herbs.
Or make willow sprout egg cake.
